Here is some of the science of the antibiotic resistance cycle. Click the link for the full paper.
Evidence of resistance associated with antimicrobial growth promotants has been emerging over the past three decades. Tetracycline-resistant organisms were found in 1976 in chickens raised on feed supplemented with tetracycline, a human-use antibiotic. In a prospective study of 11 poultry farm members and 24 neighbors, Levy and co-workers (1976a) found that before the use of tetracycline on the farm neither the farmers nor the animals were positive for tetracyclineresistant intestinal flora. Within 5 months of the introduction of tetracycline in the poultry feed, 31.3% of fecal samples from farm members harbored intestinal flora that were resistant to tetracycline even though none had been treated clinically with tetracycline. Tetracycline-resistant bacteria were found in only 6.8% of the samples from neighbors
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