MRSA ST398 in food animals could evolve

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in MRSA ST398 Infection Patterns

Writing in Clinical Microbiology and Infection, Dr. Jan Kluytmans of Amphia Hospital in Breda, the Netherlands, recounts the identification of MRSA multilocus sequence type 398 (or ST398). On Dutch farms, from 23% to 81% of pigs have been found colonized with the strain, carrying it without being made sick by it. When farmers on those farms were surveyed, they were colonized with an identical strain.

ST398 appears to be less virulent and less transmissible than the community-associated strains of MRSA common in the United States, which have very low prevalence in the Netherlands. “The impact of ST398 on [human] public health may be limited,” Kluytmans writes, “but close monitoring of its evolution over time will be required.”

The strain’s presence in meat after slaughter—it has been found in beef, lamb, and chicken and other birds in addition to pork—raises uncertainties over the degree of its movement into the food chain. While staph species are known to cause staphylococcal food poisoning, MRSA ST398 to date lacks the toxin-producing genes that would produce similar illness.

The chief concern, Kluytmans writes, is the possibility that people preparing MRSA-contaminated meat for cooking will become colonized with the organism on their skin or mucous membranes, moving it into a broad new ecological niche and positioning it as a possible cause of further human infections.

via CIDRAP >> MRSA clone in food animals worrisome, expert says.

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